Clinically proven proprietary nitric oxide (NO)-based technology platform
Our innovative NITRICIL™ technology leverages nitric oxide’s naturally occurring antimicrobial and immunomodulatory effects to develop new therapies for unmet medical needs across multiple therapeutic areas. NITRICIL™ stores the gaseous NO species on large polymers, which allow nitric oxide to be applied as timed-release chemical entities. This technology allows us to control the level of nitric oxide storage, the rate of release, and the molecule size for targeted delivery. The result is stabilized, druggable nitric oxide that is optimized for a specific indication.

Leveraging the Naturally Occurring Antiviral and Immunomodulatory Effects of Nitric Oxide “NO”

Tunable Dosing Enables Proprietary Formulations That Target Each Indication

Where You Need It

Engineering the molecule’s geometry and size allows us to focus delivery on specific tissues and limit off-target effects.


In the Amount You Need

Controlling the concentration of nitric oxide dictates its ability to do everything from killing viruses and bacteria to reducing pain and inflammation while promoting healing.


When You Need It Most

The ability to manipulate the rate of release can “turn on” or “turn off” physiological events with a single agent. We believe this is perhaps the most important attribute in unlocking nitric oxide’s therapeutic potential.

If you are a healthcare provider with a specific medical question related to Novan products please contact our medical affairs team at